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Koichi Tsuneyama Selected Research

Inflammatory Bowel Diseases (Inflammatory Bowel Disease)

1/2023Establishment of a Novel Colitis-Associated Cancer Mouse Model Showing Flat Invasive Neoplasia.
1/2014Differential modulation by IL-17A of Cholangitis versus Colitis in IL-2Rα deleted mice.
7/2010Deletion of interleukin-6 in mice with the dominant negative form of transforming growth factor beta receptor II improves colitis but exacerbates autoimmune cholangitis.
1/2009Differential mechanisms in the pathogenesis of autoimmune cholangitis versus inflammatory bowel disease in interleukin-2Ralpha(-/-) mice.
6/2008Adoptive transfer of CD8(+) T cells from transforming growth factor beta receptor type II (dominant negative form) induces autoimmune cholangitis in mice.

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Koichi Tsuneyama Research Topics

Disease

55Inflammation (Inflammations)
12/2023 - 08/2002
46Neoplasms (Cancer)
06/2023 - 10/2003
42Biliary Liver Cirrhosis (Primary Biliary Cirrhosis)
01/2023 - 08/2002
35Non-alcoholic Fatty Liver Disease
07/2023 - 10/2006
32Fibrosis (Cirrhosis)
12/2023 - 12/2003
25Cholangitis
01/2023 - 08/2007
21Obesity
04/2024 - 02/2008
20Carcinogenesis
04/2023 - 09/2006
18Hepatocellular Carcinoma (Hepatoma)
10/2022 - 03/2005
17Liver Cirrhosis (Hepatic Cirrhosis)
04/2024 - 01/2006
17Fatty Liver
04/2024 - 10/2006
16Metabolic Syndrome (Dysmetabolic Syndrome X)
04/2024 - 03/2010
15Body Weight (Weight, Body)
12/2023 - 10/2006
15Carcinoma (Carcinomatosis)
01/2022 - 02/2003
14Neoplasm Metastasis (Metastasis)
01/2023 - 09/2006
13Chemical and Drug Induced Liver Injury
11/2019 - 10/2009
12Alcoholic Fatty Liver
12/2023 - 03/2008
11Autoimmune Diseases (Autoimmune Disease)
01/2023 - 01/2003
10Liver Diseases (Liver Disease)
12/2023 - 11/2009
10Insulin Resistance
01/2023 - 11/2009
9Colitis
01/2023 - 03/2009
9Type 2 Diabetes Mellitus (MODY)
12/2018 - 02/2008
7Cholangiocarcinoma
12/2021 - 02/2003
7Infections
10/2019 - 08/2007
6Necrosis
01/2023 - 01/2004
6Adenocarcinoma
01/2023 - 09/2006
6Adenoma (Adenomas)
01/2022 - 11/2006
5Inflammatory Bowel Diseases (Inflammatory Bowel Disease)
01/2023 - 06/2008
5Hypersensitivity (Allergy)
01/2017 - 03/2010
5Hyperlipidemias (Hyperlipidemia)
01/2017 - 01/2011
4Hepatitis
01/2023 - 02/2010
4Disease Progression
01/2022 - 01/2012
4Chronic Hepatitis C
12/2021 - 04/2006
4Cholestasis
12/2019 - 07/2003
4Diabetes Mellitus
11/2019 - 09/2009
4Wounds and Injuries (Trauma)
01/2018 - 10/2012
4Squamous Cell Carcinoma (Epidermoid Carcinoma)
06/2011 - 01/2002
4Stomach Neoplasms (Stomach Cancer)
12/2007 - 09/2006
4Lymphatic Metastasis
01/2007 - 09/2006
3Hyperphagia (Overeating)
04/2024 - 09/2009
3Autoimmune Hepatitis
01/2023 - 04/2006
3Colorectal Neoplasms (Colorectal Cancer)
01/2023 - 05/2007
3Polyps
01/2022 - 05/2014
3Virus Diseases (Viral Diseases)
12/2021 - 10/2011

Drug/Important Bio-Agent (IBA)

24CytokinesIBA
01/2023 - 01/2003
22Proteins (Proteins, Gene)FDA Link
01/2023 - 07/2003
20CholesterolIBA
04/2024 - 07/2003
14AutoantibodiesIBA
10/2022 - 01/2003
14AntibodiesIBA
01/2022 - 06/2008
12Messenger RNA (mRNA)IBA
01/2023 - 03/2004
12LipidsIBA
01/2022 - 01/2006
12Sodium Glutamate (Accent)IBA
02/2020 - 02/2008
9Biomarkers (Surrogate Marker)IBA
07/2022 - 01/2012
8Glucose (Dextrose)FDA LinkGeneric
12/2023 - 03/2008
8Bile Acids and Salts (Bile Acids)IBA
02/2023 - 02/2012
8MucinsIBA
01/2017 - 10/2002
7CholatesIBA
04/2024 - 01/2013
7ChemokinesIBA
01/2023 - 09/2005
7DNA (Deoxyribonucleic Acid)IBA
10/2019 - 01/2005
7Interleukin-17 (Interleukin 17)IBA
12/2018 - 02/2009
7AntigensIBA
12/2018 - 03/2004
6Insulin (Novolin)FDA Link
12/2023 - 10/2006
6Glutamate-Ammonia Ligase (Glutamine Synthetase)IBA
10/2022 - 06/2014
6Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
12/2016 - 09/2006
6InterleukinsIBA
06/2014 - 11/2009
6Transforming Growth Factor beta Receptors (TGF beta Receptors)IBA
10/2012 - 06/2008
6Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
02/2010 - 06/2008
5CollagenIBA
12/2023 - 10/2002
5AutoantigensIBA
01/2023 - 03/2008
5Transforming Growth Factors (Transforming Growth Factor)IBA
06/2022 - 02/2013
5MicroRNAs (MicroRNA)IBA
12/2020 - 01/2012
5EnzymesIBA
05/2018 - 10/2009
5Interferon-gamma (Interferon, gamma)IBA
01/2018 - 06/2008
5Chemokine ReceptorsIBA
01/2017 - 11/2002
5Receptor for Advanced Glycation End ProductsIBA
04/2013 - 10/2005
4CarcinogensIBA
06/2023 - 02/2007
4Cholic AcidIBA
08/2022 - 02/2012
4Choline (Choline Chloride)IBA
12/2021 - 01/2012
4Indicators and Reagents (Reagents)IBA
12/2021 - 09/2006
4Streptozocin (Streptozotocin)FDA Link
09/2021 - 07/2014
4LigandsIBA
01/2021 - 06/2007
4Volatile Fatty AcidsIBA
02/2020 - 01/2017
4Small Interfering RNA (siRNA)IBA
01/2019 - 08/2007
4Immunoglobulins (Immunoglobulin)IBA
10/2014 - 10/2005
4XenobioticsIBA
08/2014 - 08/2007
4Acetaminophen (Paracetamol)FDA LinkGeneric
08/2014 - 01/2004
4Interleukin-12 (IL 12)IBA
06/2014 - 10/2012
4Galectin 3 (LGALS3)IBA
01/2012 - 01/2006
4Tumor Viral Antigens (Large T Antigen)IBA
04/2008 - 01/2007
3Anti-Bacterial Agents (Antibiotics)IBA
02/2023 - 01/2015
3Dihydrotachysterol (AT 10)IBA
01/2023 - 01/2004
3CateninsIBA
01/2023 - 08/2016
3Alanine Transaminase (SGPT)IBA
01/2023 - 07/2015
3beta CateninIBA
10/2022 - 12/2007
3Transaminases (Aminotransferases)IBA
01/2022 - 11/2009
3Methionine (L-Methionine)FDA Link
12/2021 - 12/2013

Therapy/Procedure

20Therapeutics
10/2022 - 01/2006
18Drug Therapy (Chemotherapy)
12/2021 - 10/2009
4Kampo Medicine (Kampo)
10/2012 - 03/2008
3Lasers (Laser)
12/2023 - 06/2007